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![]() ![]() kupanie v vanne _Ex: to take (to have) one's tub prinimat' vannu _Ex: a cold tub would do him good emu bylo by polezno prinyat' holodnuyu vannu _Ex: there's nothing like a cold tub to refresh you nichto tak ne osvezhaet, kak holodnaya vannaĦ> uchebnaya shlyupka _Ex: fixed tub zachal'naya lodka s zerkalom na rumpeleħ> _razg. vanna _Ex: he jumped into his tub on vlez v vannuĥ> _razg. PGsearchġ> lohan', ushat bad'ya chan, bak, bachok _Ex: tub wheel baraban v stiral'noi mashine _Ex: a metal tub for washing linen zheleznoe koryto dlya stirki bel'yaĢ> kadka, bochonok _Ex: tub gardening vyrashivanie rastenii v kadkah, kadochnaya kul'tura _Ex: tub plant kadochnoe rastenie _Ex: to plant (to put) trees in tubs sazhat' derev'ya v kadkahģ> bochonok (kak mera emkosti) _Ex: a tub of water bochonok vodyĤ> _razg. By understanding how factors like ONA backbone charge, backbone flexibility, and ONA-star polymer conjugate architecture impact the behavior of ONA-star polymer conjugate systems, we can better inform how the selection of ONA chemistry will influence resulting ONA-star polymer assembly. ![]() While the number of arms in the ONA-star polymer conjugate has a negligible effect on the ONA T m in these systems, as the number of ONA-star polymer arms increase, the assembly temperature T a increases and local ordering in the assembled state improves. Similar behavior is seen for the assembly transition temperature (T a ) with varying ONA backbone charge and flexibility. The melting temperature (T m ) of the ONA strands decreases upon going from a neutral to a charged ONA backbone and upon increasing flexibility of the ONA backbone. Additionally, we characterize the assembly of the ONA-star polymer conjugates by tracking cluster formation and percolation as a function of temperature, as well as cluster size distribution at temperatures near the assembly transition region. ![]() We quantify the thermo-reversible behavior of the ONA-star polymer conjugates by quantifying the hybridization of the ONA strands in the system as a function of temperature (i.e. In this work, we conduct coarse-grained molecular simulations of ONA-star polymer conjugates with varying ONA backbone flexibility, ONA backbone charge, and number of arms in the star polymer at a constant ONA strand volume fraction to elucidate the effect of these design parameters on the thermodynamics and assembly of multi-arm ONA-star polymer conjugates. Understanding the impact of incorporating new physical and chemical features in oligomeric DNA mimics, termed generally as 'oligonucleic acids' ( ONAs), on their structure and thermodynamics will be beneficial in designing novel materials for a variety of applications. ![]()
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